Welcome to SEED -- preliminary Screening-Enrichment analysis-Eliminate irrelevant genes-develop a model

Cancer Immunity Cycle

SEDM is a tool that utilizes RNAseq expression matrices in combination with multiple prognostic indicators. It applies machine learning and gene function analysis to identify potential tumor gene signatures from high-dimensional RNAseq data.

This platform allows you to:

  • Identify Tumor Gene Signatures: Use RNAseq expression data combined with prognostic indicators to find potential gene signatures linked to tumor prognosis.
  • Analyze Datasets and Select Features: Preprocess data, perform dimensionality reduction, and select key features to discover meaningful gene expression patterns.
  • Build and Validate Machine Learning Models: Develop models to predict the prognostic value of genes and validate them using single-cell sequencing and mIHC data.

How to Cite

If you use SEDM in your work, please cite the following publication:





The result files are as follows:

Download Result of Data Split




The result files are as follows:

Download the modified file




The merged results are as follows:

Download the merged file




The Lasso analysis results are as follows:

Download the Lasso analysis results




The results are as follows:

Download the intersection file




The results are as follows:

Download the analyzed results.